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4-Methylmethcathinone (also known as 4-MMC, M-CAT, drone, meow meow, and mephedrone[1]) is a novel entactogen-stimulant substance of the cathinone class. Mephedrone belongs to a group known as the substituted cathinone, which are derivatives of the active ingredient in the khat plant (Catha edulluis). Buy R-MMC Online


Mephedrone was first synthesized in 1929, but did not become widely known until it was rediscovered in 2003. By 2007, it was reporte to be available for sale on the internet, by 2008 law enforcement agencies had become aware of the compound, and by 2010 it had been reporte in most of Europe, becoming particularly prevalent in the United Kingdom.


It comes in the form of tablets or a powder, which users can swallow, snort, inject or insert rectally, producing effects which are somewhat similar to those of MDMA, amphetamine, and cocaine. It is reporte to produce a mixture of classic stimulant and entactogenic effects effects reminiscent of cocaine and MDMA.

Research Chemicals of mephedrone 4 mmc

Mephedrone, or 4-methylmethcathinone, is a synthetic molecule of the cathinone family. Cathinones are structurally similar to amphetamines, they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines and cathinones are alpha-methylated phenethylamines, cathinones contain an additional carbonyl group at R1. Mephedrone contains an additional methyl substitutions at RN, similarly to MDMA and methamphetamine, and R4 of its phenyl ring.


Pharmacology of Mephedrone 4MMC

Several articles published near the end of 2011 examined the effects of mephedrone in the brains of rats. As well as examining the reinforcing potential of mephedrone. Dopamine and serotonin were collectedd using microdialysis, and increases in dopamine and serotonin were measure. Mephedrone administration cause about a 500% increase in dopamine, and about a 950% increase in serotonin. They reached their peak concentrations at 40 minutes and 20 minutes and returned to baseline by 120 minutes after injection.


Analysis of the ratio for dopamine and serotonin indicated mephedrone was preferentially a serotonin releaser. With a ratio of 1.22:1 (serotonin vs. dopamine). Additionally, half-lives for the decrease in dopamine and serotonin were calculate and found to have decay rates of 24.5 minutes and 25.5 minutes.

These findings show mephedrone induces a massive increase in both dopamine and serotonin, combined with rapid clearance. This increase in neurotransmitters provides an explanation for the euphoric and stimulating subjective effects induced by this experience.


Mephedrone (4-MMC / 4-methylmethcathinone)

is a well-known cathinone that acts as a stimulant and empathogenic for mephedrone / 4-MMC. And is among the research chemicals that have been illegalized in most countries worldwide for several years.
4-MMC reached a very high popularity status, after the prohibition it is still on the black market to find. But ostensibly the quality should not be able to keep up with the mephedrone before the ban (the so-called Pre-Ban Mephedrone). According to many consumers who took mephedrone before the illegalization of the current 4-MMC cause a much less strong & euphoric effect, which should not be compensated by increasing the dose.


It is certain that there are strong differences in the quality of the available mephedrone, since the synthesis as well as amphetamine, MDMA & co. can only be done illegally and accordingly unregulated.

The effect of mephedrone may be considered to be comparable to cocaine, but it is more empathogenic than egopushing.

The euphoric effect is usually much more noticeable than the stimulating one. The more it is refilledd, the weaker is the euphoria.

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